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BonnGut Research Group

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Welcome to BonnGut research group

           A major factor linking the daily diet with human physiology and pathology that has emerged in recent years is the entirety of microorganisms (microbiota) colonising the human intestine. In particular, it has been hypothesised recently that the intestinal microbiome affects signalling along the “gut-brain-axis” to alter neurological processes in the host. The aim of the BonnGut group is to systematically analyse the impact of commensal microorganisms and their metabolites on the link between nutrition and cognition, with the goal of establishing causative connections between diet, microbiota, metabolism and brain function. To achieve this aim, the BonnGut pursues a translational approach with mechanistic studies in humans and mouse models. Finally in synergy with the general DietBB cluster [www.diet-body-brain.de/home.html], the fundamental approach taken by the BonnGut will be to identify associations between the intestinal microbiome, dietary patterns or food intake, and cognitive function across the lifespan in order to define a healthy microbiota and based on this personalised dietary recommendations and treatments.

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